USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: SAMP_HUMAN USC-OGP 2-DE database:  SAMP_HUMAN SAMP_HUMAN General information about the entry View entry in simple text format Entry name SAMP_HUMAN Primary accession number P02743 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Serum amyloid P-component; Short=SAP; AltName: Full=9.5S alpha-1-glycoprotein; Contains: RecName: Full=Serum amyloid P-component(1-203); Flags: Precursor;. Gene name Name=APCS Synonyms=PTX2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0507: pI=5.37; Mw=27181 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0790: pI=5.33; Mw=29909 Cross-references UniProtKB/Swiss-Prot P02743; SAMP_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SAMP_HUMAN Primary accession number P02743 Sequence was last modified on  February 1, 1995 (version 2) Annotations were last modified on  March 15, 2017 (version 193) Name and origin of the protein Description RecName: Full=Serum amyloid P-component; Short=SAP; AltName: Full=9.5S alpha-1-glycoprotein; Contains: RecName: Full=Serum amyloid P-component(1-203); Flags: Precursor; Gene name Name=APCS Synonyms=PTX2 Encoded on Name=APCS; Synonyms=PTX2 Keywords 3D-structure; Amyloid; Calcium; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Lectin; Metal-binding; Polymorphism; Reference proteome; Secreted; Signal. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D00097; BAA00060.1; -; Genomic_DNA EMBL M10944; AAA60302.1; -; mRNA EMBL X04608; CAA28275.1; -; mRNA EMBL CR450313; CAG29309.1; -; mRNA EMBL AL445528; CAH73651.1; -; Genomic_DNA EMBL BT006750; AAP35396.1; -; mRNA EMBL BC007039; AAH07039.1; -; mRNA EMBL BC007058; AAH07058.1; -; mRNA CCDS CCDS1186.1; -; . PIR A25503; YLHUP; . RefSeq NP_001630.1; NM_001639.3; . UniGene Hs.507080; -; . PDB 1GYK; X-ray; 2.20 A; A/B/C/D/E=20-223 PDB 1LGN; X-ray; 2.80 A; A/B/C/D/E=20-223 PDB 1SAC; X-ray; 2.00 A; A/B/C/D/E=20-223 PDB 2A3W; X-ray; 2.20 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T=20-223 PDB 2A3X; X-ray; 3.00 A; A/B/C/D/E/F/G/H/I/J=20-223 PDB 2A3Y; X-ray; 2.00 A; A/B/C/D/E=20-223 PDB 2W08; X-ray; 1.70 A; A/B/C/D/E=20-223 PDB 3D5O; X-ray; 2.80 A; A/B/C/D/E=20-223 PDB 3KQR; X-ray; 1.50 A; A/B/C/D/E=20-223 PDB 4AVS; X-ray; 1.40 A; A/B/C/D/E=20-223 PDB 4AVT; X-ray; 3.20 A; A/B/C/D/E/F/G/H/I/J=20-223 PDB 4AVV; X-ray; 1.60 A; A/B/C/D/E=20-223 PDB 4AYU; X-ray; 1.50 A; A/B/C/D/E=20-223 PDBsum 1GYK; -; . PDBsum 1LGN; -; . PDBsum 1SAC; -; . PDBsum 2A3W; -; . PDBsum 2A3X; -; . PDBsum 2A3Y; -; . PDBsum 2W08; -; . PDBsum 3D5O; -; . PDBsum 3KQR; -; . PDBsum 4AVS; -; . PDBsum 4AVT; -; . PDBsum 4AVV; -; . PDBsum 4AYU; -; . ProteinModelPortal P02743; -; . SMR P02743; -; . BioGrid 106822; 13; . DIP DIP-46911N; -; . IntAct P02743; 6; . MINT MINT-4723480; -; . STRING 9606.ENSP00000255040; -; . ChEMBL CHEMBL4929; -; . GuidetoPHARMACOLOGY 2839; -; . TCDB 1.C.92.1.2; the pentraxin (pentraxin) family; . iPTMnet P02743; -; . PhosphoSitePlus P02743; -; . UniCarbKB P02743; -; . BioMuta APCS; -; . DMDM 730704; -; . DOSAC-COBS-2DPAGE P02743; -; . OGP P02743; -; . REPRODUCTION-2DPAGE IPI00022391; -; . REPRODUCTION-2DPAGE P02743; -; . SWISS-2DPAGE P02743; -; . PaxDb P02743; -; . PeptideAtlas P02743; -; . PRIDE P02743; -; . DNASU 325; -; . Ensembl ENST00000255040; ENSP00000255040; ENSG00000132703; . GeneID 325; -; . KEGG hsa:325; -; . CTD 325; -; . DisGeNET 325; -; . GeneCards APCS; -; . HGNC HGNC:584; APCS; . HPA CAB007817; -; . HPA HPA053294; -; . MIM 104770; gene; . neXtProt NX_P02743; -; . OpenTargets ENSG00000132703; -; . PharmGKB PA24877; -; . eggNOG ENOG410J1FD; Eukaryota; . eggNOG ENOG410YN8S; LUCA; . GeneTree ENSGT00760000119128; -; . HOGENOM HOG000247043; -; . HOVERGEN HBG005405; -; . InParanoid P02743; -; . OMA DHVNLIT; -; . OrthoDB EOG091G0H6X; -; . PhylomeDB P02743; -; . TreeFam TF330208; -; . Reactome R-HSA-977225; Amyloid fiber formation; . ChiTaRS APCS; human; . EvolutionaryTrace P02743; -; . GeneWiki Serum_amyloid_P_component; -; . GenomeRNAi 325; -; . PRO PR:P02743; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000132703; -; . CleanEx HS_APCS; -; . ExpressionAtlas P02743; baseline and differential; . Genevisible P02743; HS; . GO GO:0072562; C:blood microparticle; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; NAS:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:BHF-UCL; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005509; F:calcium ion binding; IDA:BHF-UCL; . GO GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW; . GO GO:0001849; F:complement component C1q binding; IDA:BHF-UCL; . GO GO:0051082; F:unfolded protein binding; TAS:ProtInc; . GO GO:0046790; F:virion binding; IDA:BHF-UCL; . GO GO:0006953; P:acute-phase response; TAS:ProtInc; . GO GO:0044267; P:cellular protein metabolic process; TAS:Reactome; . GO GO:0051131; P:chaperone-mediated protein complex assembly; TAS:ProtInc; . GO GO:0045087; P:innate immune response; IDA:BHF-UCL; . GO GO:0044869; P:negative regulation by host of viral exo-alpha-sialidase activity; IDA:BHF-UCL; . GO GO:0044871; P:negative regulation by host of viral glycoprotein metabolic process; IDA:BHF-UCL; . GO GO:0002674; P:negative regulation of acute inflammatory response; IC:BHF-UCL; . GO GO:1903016; P:negative regulation of exo-alpha-sialidase activity; IDA:BHF-UCL; . GO GO:1903019; P:negative regulation of glycoprotein metabolic process; IDA:BHF-UCL; . GO GO:0045656; P:negative regulation of monocyte differentiation; IDA:BHF-UCL; . GO GO:0046597; P:negative regulation of viral entry into host cell; IDA:BHF-UCL; . GO GO:0048525; P:negative regulation of viral process; IDA:BHF-UCL; . GO GO:0061045; P:negative regulation of wound healing; IC:BHF-UCL; . GO GO:0006457; P:protein folding; TAS:ProtInc; . CDD cd00152; PTX; 1; . Gene3D 2.60.120.200; -; 1; . InterPro IPR013320; ConA-like_dom; . InterPro IPR030476; Pentaxin_CS; . InterPro IPR001759; Pentraxin-related; . Pfam PF00354; Pentaxin; 1; . PRINTS PR00895; PENTAXIN; . SMART SM00159; PTX; 1; . SUPFAM SSF49899; SSF49899; 1; . PROSITE PS00289; PTX_1; 1; . PROSITE PS51828; PTX_2; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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